Evaluation of the cultivation age of dried ginseng radix and its commercial products by using 1H-NMR fingerprint analysis
Journal
The American Journal of Chinese Medicine
Journal Volume
38
Journal Issue
1
Pages
205-218
Date Issued
2010
Date
2010
Author(s)
Wen-Neng Lin
Hsiu-Ying Lu
Meng-Shiou Lee
Shih-Ying Yang
Hsi-Jien Chen
Yuan-Shiun Chang
Wen-Te Chang
Abstract
The perfect ginseng radix is collected when the ginseng root reaches a cultivation age of six years; this ensures the best mass quality and consistency of the plant's essential bioactive components. Since traditional means of authentication via physical appearance or smell are hardly reliable, an efficient analytical method that can determine the real cultivation age of dried ginseng radix in commercial products, especially ginseng products of various dosage forms, is urgently required. In the present study, chemical fingerprint by 1H-NMR spectroscopy was used on dried ginseng radix samples with cultivation ages ranging from 1–6 years. The resulting dataset was then analyzed by using principle component analysis and cluster analysis to build up a distributive model that allows the identification of the real cultivation age of the ginseng radix based on a plant metabolomic strategy. This quality surveillance method was able to clearly discriminate the 6 years old ginseng radix from the other ages, and could be applied on the evaluation of the real cultivation age for the various dried white ginseng radix samples and commercial products accurately.
Subjects
Ginseng
Cultivation Age
Metabolomic
NMR
Principal Component Analysis
Cluster Analysis
Publisher
World Scientific
Type
journal article