Anti-oxidant activity and effect of Pinus morrisonicola Hay. on the survival of leukemia cell line U937
Journal
Phytomedicine
Journal Volume
12
Journal Issue
9
Pages
663-669
Date Issued
2005-09
Author(s)
T.-Y. Hsu
S.-C. Sheu
E.-T. Liaw
T.-C. Wang
C.-C. Lin
Abstract
The free radical scavenging and anti-cancer activites of Pinus morrisonicola Hay. were studied using different parts of the pine, namely, needle, bark and cone. Results showed that pine needle water extract has the highest scavenging superoxide anion activity and the lowest IC50 Value in inhibiting superoxide anion formation; however, the bark water extract showed the best anti-lipid peroxidation activity. Additionally, needle water extract displayed the highest inhibition of leukemia cell line U937 growth. The results indicated that P. morrisonicola Hay. possesses potential chemopreventative and therapeutic properties.
Subjects
anti-oxidant activity
lipid peroxidation
cytotoxicity
leukemia
Publisher
Elsevier
Type
journal article