薑黃對大鼠28天餵飼之安全性

Other Title
Safety Evaluation of Turmeric (Curcuma longa L.) Powder via Oral Gavage for 28 days in Rats
Resource
植物保護學會會刊 45(3): 237-255
Journal
植物保護學會會刊
Journal Volume
45
Journal Issue
3
Pages
237-255
Date Issued
2003-09
Date
2003-09
Author(s)
廖俊旺
王順成
黃振聲
Liao, J. W.
Wang, S. C.
Hwang, J. S.
DOI
URI
Abstract
Turmeric (Curcuma longa Linn.) contains curcumin that has antioxidative effects on inflammatory and hepatic disorders, and inhibits carcinogen-induced cancers in animal models. However, the chronic effect of turmeric is a concern of the WHO/FAO. The objective of this study was to evaluate the oral acute and 28-day feeding toxicity of turmeric powder (TP) in Sprague-Dawley (SD) rats. Results revealed that the acute oral LD50 of TP was greater than 5000 mg/kg body weight (bw) in rats. In addition, the TP was administered by daily gavage in rats at doses of 0, 100, 500, and 1000 mg/kg bw for 28 days.
Subjects
薑黃
28天餵飼安全性
大鼠
turmeric tuber
28-day feeding toxicity
rats
Publisher
中華植物保護學會
Type
journal article
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