天麻之藥效研究進展
Other Title
Recent Pharmacodynamic Study of Gastrodia Elata
Start Page
87
End Page
101
ISBN
957-02-4205-1
Date Issued
1999-03
Date
1999-03
Author(s)
謝明村
吳啟瑞
Hsieh Ming-Tsuen
Wu Chi-Rel
Abstract
天麻（赤箭）始載於神農本草經，主治「肝風內動之頭痛、頭暈目眩；現代藥理學研究指出具抗痙攣、鎮靜、鎮痛及降壓作用。本研究擬針對智力強化作用，開發天麻及其活性成分之新藥效。天麻粗抽物可改善學習記憶障礙，分離成分中天麻苔（gastrodin）及天麻普元（P-hydroxybenzyl alcohol）亦具改善作用，且以天麻元為佳；而其作用亦較智力強化藥Piracetam為佳。
Gastrodia elata (GE), described in Sheng-Nung-Pen-Tsao-Ging, was used to cure headache and dizziness caused by hypertension. Recent pharmacological reports suggested GE possessed anticonvulsive, sedative, analgesic and antihypertensive effects. The present study was attempted to vealuate the new (cognitiveenhancing) effects of GE and its constituents. GE extract significantly counteracted the memory inpairment. Gastrodin and p-hydroxybenzyl alcohol(HBA) were isolated from GE extract and also significantly counteracted the memory impairment. The counteracting effect of HBA was greater than that of gastrodin and nootropics piracedam.
Event(s)
1999藥用植物之開發與利用研討會
Proceedings of the Symposium on Development and Utilization of Medicinal Plants 1999
Publisher
農業試驗所
Type
book part
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