Constituents from Formosan Peucedanum japonicum

Abstract

Three new khellaotone esters, (-) -trans-3’-acetyl-4’-senecioyl-khellactone, (±) -cis-4’-tigloylkhellactone, (+ ) -trans-4’-tigloylkhel-Iactone. together with 14 known coumarins, isoimperatorin, psoralen, bergapten, xanthotoxol, onidilin, (-)-selinidin, (-)-deltoin, (+)-pteryxin, (+)-peucedanocoumarin III, xanthotoxin, imperatorin, ( + ) -marmesin, (+) -oxypeucedanin hydrate, (+) -peucedanol and three chromones, eugenin, (-)-hamaudol, (+)-visamminol, have been isolated from the root of Formosan Peucedanum japonicum (Umbelliferae). The structures of the new compounds were elucidated by spectral data. 對台灣產繳形科(Umbelliferae)植物牡丹防風(Peucedanum jamnicum)根部進行化學成分研究，由皮部之甲醇抽出液以CHC13與H2O進行分配，所得之CHC13層進行分離迄今得到14種已知香豆素類化合物：isoimperatorin, psoralen, bergapten, xanthotoxol, cnidilin, (-)-sellnidin, (-)-deltoin, (+)-pteryxin, (+)-peucedanocoumarin III, xanthotoxin, imperatorin, (+)-marmesin, (+)-oxypeucedanin hydrate, (+)-peucedanol, 3種chromone類化合物：eugenin, (-)-hamaudol, (+)-visamminol，及3種新khellactone esters化合物：(-)-trans-3’-acetyl-4’-senecioylkhellactone,(±)-cis-4’-tigloylkhellactone, (+)-trans-4’-tigloylkhel-1actone，這些化合物之結構皆以光譜數據而決定。