A Comparative Pharmacognostic Study of Taiwanese and Commercial Articles of Phellodendri Cortex
Other Title
台灣黃蘗及市售黃蘗之比較生藥學研究
Journal
臺灣地區藥用植物資源之開發與利用學術研討會專刊
Part Of
農業試驗所特刊第48號
Pages
328-338
ISBN
957-00-5319-4
Date Issued
1995-04
Date
1995-04
Author(s)
Hsien-Chang Chg
Shiow-Hua Chiou
Yuh-Pan Chen
Ying-Mei Liu
Shuenn-Jyi Sheu
張憲昌
邱秀華
陳玉盤
劉英玫
許順吉
Abstract
Phellodendri Cortex was first recorded in Shen-nung’s Herbal and has been used as a bitter stomachic ever since. The drug is derived from the trunk bark of plants of the rutaceous Phellodendron genus. A total of 31 commercial samples of Phellodendri Cortex from the origins of Plellodendron amurense Ruprecht, P.chinense Schneid, P.wilsonii Hayata et Kanehira and P.amurense Rupr. var. sachalinense Fr. Schn. respectively were collected from the Taiwan and Japan herbal markets. The contents of the five quaternary alkaloids-berberine, palmatine,jatrorrhizine,phellodndrine and magnoflorine in these samples were determined by capillary electrophoresie. It was found that P.wilsonii(4.10±0.78%)and P.amurense var. sachalinense (4.18±1.03%)were superior to P.amurense(1.55±0.72%)and P.chinense(1.54±0.60%).Berberine was of the highest content in almost all damples. It occupied about
80% of the total alkaloids in the first two of the four herbs named above, but only about 40% in the latter two. From the data of chemical analysis of an herb’s constituents and from the herb’s texture and color, we can postulate the origin and quality of the herb.
黃蘗(Phellodendri Cortex)始載於《神農本草經》列為中品藥,為苦味健胃劑,用為治熱痢泄瀉、黃疸、痔瘡、便血、淋濁、帶下、瘡瘍等症。其來源主要為芸香料(Rutaceae)植物黃蘗(Phellodendron amurense Ruprecht)、川黃蘗(P. shinense Schneid)、台灣黃蘗(P. wilsonii Hay. et Kanehira)及其同屬近緣植物之幹皮。
為了解目前市售黃蘗之種類,並評價其品質,以供為用藥之依據,本研究由台灣及鄰近地區,搜集市售樣品計31件,以生藥組織學之方法鑑定其來源,並配合毛細管電泳法定量其成分。
由組織之鑑定結果,關黃蘗Phellodendron amurense Ruprecht有4件,川黃蘗P. shinense Schneid有14件,台灣黃蘗P. wilsonii Hay. et Kanehira有7件,日本黃蘗P. amurense Rupr. Var. Fr. Schm.有6件。
五種生物鹼成分為berberine, plmatine, jatrorrhizine, phelldendrine and magnoflorine等,由毛細管電泳法定量結果,台灣黃蘗(4.10±0.78%)及日本黃蘗(4.18±1.03%)含量高於關黃蘗(1.55±0.72%)及川黃蘗(1.54±0.60%)。而berberine之含量在這些藥材中均相當高,其中以台灣黃蘗及日本黃蘗含量約佔全生物鹼之80%,而關黃蘗及川黃蘗則約佔40%。台灣黃蘗品質頗佳,宜加以推廣栽培。
Event(s)
臺灣地區藥用植物資源之開發與利用學術研討會
Proceeding of A Symposium on Development and Utilization of Resources of Medicinal Plants in Taiwan
Subjects
Phellodendri Cortex
capillary electrophoresis
histological identification
berberine alkaloids
Publisher
農業試驗所
Type
conference paper
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